基于儿科古文献的中药药物警戒思想与药学服务思考

doi:10.19803/j.1672-8629.2022.06.02

中国药物警戒 ›› 2022, Vol. 19 ›› Issue (6): 591-594.
DOI: 10.19803/j.1672-8629.2022.06.02

• 特殊人群的中药药物警戒与药学服务专栏 • 上一篇下一篇

基于儿科古文献的中药药物警戒思想与药学服务思考

王晓芳^1,2, 张晓朦^1,2, 张冰^1,2,*, 林志健^1,2, 韦昌策¹

¹北京中医药大学中药学院,北京 102488;
²北京中医药大学中药药物警戒与合理用药研究中心,北京 102488

收稿日期:2022-01-28 出版日期:2022-06-15 发布日期:2022-06-13
通讯作者: ^* 张冰,女,博士,教授·博导,主任医师,中药药物警戒与合理用药研究、中药药性理论与名老中医传承研究、中药防治代谢性疾病研究。E-mail：zhangbing6@263.net
作者简介:王晓芳,女,在读硕士,中药药物警戒与合理用药。
基金资助:
国家中医药管理局国家中医药领军人才支持计划“岐黄学者”项目; 中国毒理学会临床毒理专项课题（CST2020CT501）; 国家自然科学基金资助项目（81874349）

Pharmacovigilance and pharmaceutical care of traditional Chinese medicine based on ancient pediatric literature

WANG Xiaofang^1,2, ZHANG Xiaomeng^1,2, ZHANG Bing^1,2,*, LIN Zhijian^1,2, WEI Changce¹

¹School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China;
²Center for Pharmacovigilance and Rational Use of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 102488, China

Received:2022-01-28 Online:2022-06-15 Published:2022-06-13

摘要/Abstract

摘要： 目的挖掘儿科古文献中儿童安全用药认识,为儿童特殊人群的用药警戒与药学服务提供依据。方法通过文献学方法,从《颅囟经》《小儿药证直决》《幼幼新书》《活幼心书》《幼科发挥》《幼幼集成》《幼科释谜》7部代表性儿科古文献中提取“识毒-用毒-防毒-解毒”相关警戒内容和表述。结果儿科古籍重视小儿用药安全,药物警戒认识较为系统、全面,用药以平和为旨,多从脾胃论治,从剂型、剂量、疗程、炮制、配伍等方面提升疗效,防范不良反应。结论面对临床不合理用药现象,儿科传统古籍为现代儿科开展用药警戒提供依据,指导临床安全合理用药,为药学服务开展提供方向。

关键词: 儿童, 古文献, 药物警戒, 特殊人群, 药学服务

Abstract: Objective To provide a basis for medication vigilance and pharmacy services for special pediatric populations by mining pediatric ancient literature for awareness of safe medication use in children. Methods By the methods of philology and based on the early stage of the research of "practice of cognition, application, prevention and rescue of drug toxicity" of pharmacovigilance of Chinese medicine, extract related alert expression of the Tang dynasty Luxin Jing, Song dynasty Key to Therapeutics of Children's Diseases and A New Book of Pediatrics, Yuan dynasty Huo You Xin Shu, Ming dynasty You Ke Fa Hui and Qing dynasty Collection of Words on Pediatrics, You Ke Shi Mi seven representative pediatric monographs. Results The ancient books of pediatrics paid attention to the safety of pediatric medicine, and the understanding of pharmacovigilance was more systematic and comprehensive, and the use of medicine was aimed at calmness and harmony, mostly from the spleen and stomach theory of treatment, from the dosage form, dose, course of treatment, preparation, combination and other aspects to enhanced the efficacy and prevented adverse reactions. Conclusion In the face of the phenomenon of irrational use of drugs in clinical practice, the traditional ancient books of pediatrics provide a basis for modern pediatrics to carry out pharmacovigilance, guide the safe and rational use of drugs in clinical practice, and provide direction for the development of pharmacy services.

Key words: children, ancient literature, pharmacovigilance, special population, pharmaceutical care

中图分类号:

王晓芳, 张晓朦, 张冰, 林志健, 韦昌策. 基于儿科古文献的中药药物警戒思想与药学服务思考[J]. 中国药物警戒, 2022, 19(6): 591-594.

WANG Xiaofang, ZHANG Xiaomeng, ZHANG Bing, LIN Zhijian, WEI Changce. Pharmacovigilance and pharmaceutical care of traditional Chinese medicine based on ancient pediatric literature[J]. Chinese Journal of Pharmacovigilance, 2022, 19(6): 591-594.

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基于儿科古文献的中药药物警戒思想与药学服务思考

Pharmacovigilance and pharmaceutical care of traditional Chinese medicine based on ancient pediatric literature

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