中国药物警戒 ›› 2011, Vol. 8 ›› Issue (10): 621-623.

• 药品不良反应监测 • 上一篇    下一篇

226例中药注射剂不良反应报告分析

王华1, 徐建1, 刘静静2   

  1. 1 安徽省滁州市食品药品检验所,安徽 滁州 239000;
    2 安徽全椒县食品药品监督管理局,安徽 全椒 239500
  • 收稿日期:2011-05-06 出版日期:2011-10-10 发布日期:2015-07-30
  • 作者简介:王华,女,副主任药师,药品检验和药品不良反应监测。

Analysis of 226 Cases of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections

WANG Hua1, XU Jian1, LIU Jing-jing2   

  1. 1 Chuzhou Institute for Food and Drug Control, Anhui Chuzhou 239000;
    2 Quanjiao Food and Drug Administration, Anhui Quanjiao 239500, China
  • Received:2011-05-06 Online:2011-10-10 Published:2015-07-30

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摘要： 目的 了解中药注射剂在我市发生药品不良反应的情况,为临床用药提供参考。方法 采用回顾性分析方法,对2009~2010年我市收集到的226例中药注射剂不良反应病例进行统计分析。结果 226例中药注射剂不良反应报告中,老年患者发生不良反应居首位,占40.52%。不良反应临床表现以皮肤及其附件损害最多,占33.63%;其次为全身性损害,占20.80%。不良反应涉及中药注射剂4类,以活血类品种发生率最高,占51.52%;涉及28个品种,其中双黄连注射液发生最多,占12.55%。结论 合理使用中药注射剂,加强对中药注射剂不良反应的监测,避免不合理使用造成的人体伤害。

关键词: 中药注射剂, 药品不良反应, 报告, 分析

Abstract: Objective To Understand adverse drug reactions of the Traditional Chinese Medicine Injections occurred in our city and provide alerts for clinical medicine. Methods 226 serious Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections collected by Chuzhou City during 2009~2010 were analyzed using retrospective study method. Results out of the 226 cases ADR reports,higher ADR occurrence is observed in elderly patient group,amount to 40.52% percent.The clinical expression of ADR is showed mostly skin and appendix harms, amount to 33.63% percent;secondly a general harm, amount to 20.80% percent. ADR involving four types traditional Chinese medicine injection, the highest incidence of activating blood flow types, amount to 51.52% percent; involving 28 species, most of which occurred Shuanghuanglian injection, amount to 12.55% percent. Conclusion Traditional Chinese Medicine Injection shoud be used reasonably and ADR Induced by Traditional Chinese Medicine Injections should be intensively monitored to avoid personal injury caused by irrational use.

Key words: traditional Chinese medicine injections, adverse drug reaction(ADR), report, analysis

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