92 cases of adverse drug reactions induced by risperidone tablets

doi:10.19803/j.1672-8629.2022.05.17

Abstract

Abstract: Objective To analyze the characteristics of adverse drug reactions (ADR) of risperidone tablets so as to provide reference for rational drug use. Methods Ninety-two cases of ADR caused by risperidone tablets that were collected by Xinjiang Production and Construction Corps Center for ADR Monitoring were from January 1, 2015 to December 31, 2019 analyzed. Results There were 2.29 times as many female patients as male ones. Most of the patients ranged from 18 to 44 years old (68.48%). ADR included central and peripheral nervous system diseases (51.02%), heart diseases(16.33%), gastrointestinal diseases (9.18%). Clinical manifestations included extrapyramidal disorders, tachycardia, sinus bradycardia, menstrual disorders, and abnormal liver function. Conclusion Clinicians should be alert to ADR caused by risperidone tablets in clinical practice, care for medication safety of female patients, and strengthen the training of reporting personnel so as to improve the quality of reports.

Key words: risperidone tablets, adverse drug reaction, analysis, extrapyramidal disorders

CLC Number:

R969
R994.11

JIANG Yanqiong, LIU Hongjian, LIU Xiaoxia. 92 cases of adverse drug reactions induced by risperidone tablets[J]. Chinese Journal of Pharmacovigilance, 2022, 19(5): 554-556.

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