One case of acute kidney injury induced by rifampicin

doi:10.19803/j.1672-8629.2022.04.24

Abstract

Abstract: Objective To explore ways in which acute kidney injury induced by rifampicin can be treated. Methods The process of treating one case of rifampicin-induced acute kidney injury was analyzed. The possible pathogenesis and treatments of rifampicin-induced acute kidney injury were discussed based on literature review. Results The serum creatinine was 477.2 mol·L^-1 after the second oral rifampicin. Rifampicin was immediately withdrawn and hemodialysis was performed ten times. The serum level of creatinine decreased from 579.2 mol·L^-1 to 80.6 mol·L^-1. Conclusion Rifampicin should be withdrawn immediately after acute kidney injury, and corresponding treatments should be provided according to the severity of acute kidney injury.

Key words: rifampicin, anti-tuberculous drugs, acute kidney injury, adverse drug reactions

CLC Number:

R994.11R969.3

REN Quanxia, WU Bin, HUANG Mingxia. One case of acute kidney injury induced by rifampicin[J]. Chinese Journal of Pharmacovigilance, 2022, 19(4): 453-455.

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