One case of erythema multiforme drug eruption induced by acetylcysteine capsule combined with fudosteine tablets

doi:10.19803/j.1672-8629.2022.02.23

Abstract

Abstract: Objective To explore the possible mechanism by which acetylcysteine capsules combined with fordostetin tablets cause erythema multiforme drug eruption. Methods One case of erythema multiforme drug eruption caused by oral acetylcysteine capsules combined with fordosteine tablets in February 2020 and rdlared Literature were analyzed. Results Three days after taking acetylcysteine capsules and fudosteine tablets, the patient had blisters on feet, followed by skin rupture and epidermal peeling. The same symptoms were then observed in hands, which was believed to be erythema multiform drug eruption caused by drugs. After the discontinuation of acetylcysteine capsules and fudosteine tablets, the patient's skin symptoms gradually improved. Conclusion The combined application of acetylcysteine capsules and fudosteine tablets may cause erythema multiform drug eruption, so clinicians should be alert to related adverse drug reactions.

Key words: acetylcysteine capsule, fudosteine tablets, erythema multiform drug eruption, medication safety, adverse drug reaction

CLC Number:

R969.3R994.11

WANG Xin, ZHANG Jie, ZHANG Ming, ZHANG Nan, AI Chao. One case of erythema multiforme drug eruption induced by acetylcysteine capsule combined with fudosteine tablets[J]. Chinese Journal of Pharmacovigilance, 2022, 19(2): 217-218.

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