Chinese Journal of Pharmacovigilance ›› 2022, Vol. 19 ›› Issue (11): 1242-1245.
DOI: 10.19803/j.1672-8629.20210548

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Risk investigation of insulin storage and analysis and prevention of typical insulin-related medication errors

ZHANG Qingxia1, JIANG Yongxian2△, DONG Yuexin3, XIAN Ying4, WANG Yuqin1, YAN Suying1,*   

  1. 1Department of Pharmacy, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Disease, Beijing 100053;
    2Department of Pharmacy, Sichuan Provincial Maternity and Child Health Care Hospital, Chengdu Sichuan, 610041;
    3Department of Pharmacy, Beijing Puren Hospital, Beijing 100062, China;
    4Department of Pharmacy, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing 102200, China
  • Received:2021-05-26 Published:2022-11-17

Abstract: Objective To find out about the amount of knowledge of insulin storage and the risks related to insulin storage via a questionnaire survey, and to recommend precautions. Methods The amount of knowledge of insulin storage among doctors and nurses from departments where the usage of insulin was the largest, pharmacists and patients who used insulin in Xuanwu Hospital of Capital Medical University was investigated via a questionnaire between July 18 and August 18, 2020. All the reports about insulin storage-related medication errors (MEs) from September 22, 2012 to September 30,2020 were collected from the National Monitoring Network for Clinical Safe Medication (referred to as Monitoring Network). The errors involved drugs, classification of errors, types of errors, sites of errors, people who were responsible, and causes of errors. Results A total of 93 questionnaires were collected, including 46 from health care providers and 47 from patients. All the respondents knew that insulin had to be stored at 2~ 8℃ before opening, but they did not know that insulin needed to stay away from the freezer coil. As for proper storage of insulin after opening, 20 patients (42.55%) were fully aware of the problems, and the proportion was higher than that of health care givers (34.78%). There were 16 cases of medication errors related to insulin storage in the Monitoring Network, which were mainly grade B in 11 cases (68.75%), grade C in 1 case (6.25%), grade D in 2 cases (12.50%) and grade E in 2 cases (12.50%). Among these 16 cases, 9 (56.25%) stored insulin at room temperature, 4 (25.00%) kept insulin near the freezer coil, 2 (6.25%) froze insulin when it was to be in cool storage and 2 cases (12.50%) kept insulin in cool storage when it had to be frozen. The main subjects involved in MEs were patients and their families (43.75%). Conclusion Health care providers and patients have a number of myths about insulin storage, and improper insulin storage affects blood glucose control. Therefore, attention should be paid to insulin storage to ensure the safe and effective use of insulin.

Key words: insulin, medication errors, storage, risk prevention

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