Risk difference between aristolochic acid and clinical use of traditional Chinese medicines in aristolochiaceae

doi:10.19803/j.1672-8629.20210325

Abstract

Abstract: Objective To study the difference between aristolochic acid toxicity and Aristolochiaceae in order to provide reference for rational use of toxic traditional Chinese medicines (TCM) and prevent confusion. Methods A series of problems with safe medication caused by aristolochic acid products was retrospectively analyzed through literature review. The risks of using Aristolochiaceae were summarized, and previous studies on aristolochic acid reduction were outlined. Results The problems caused by aristolochic acids were essentially different from those by Aristolochiaceae. Compliance with theories of TCM and rational use of Aristolochiaceae will not cause serious adverse reactions. Conclusion More rigorous supervision of toxic TCM are recommended. Irrational fears about the toxicity of TCM should be eliminated so as to boost the development of TCM industry.

Key words: aristolochis acids, aristolochiaceae, detoxification, scientific supervision

CLC Number:

ZHU Wenjing, ZHANG Lidan, ZHOU Yue, LEI Haimin. Risk difference between aristolochic acid and clinical use of traditional Chinese medicines in aristolochiaceae[J]. Chinese Journal of Pharmacovigilance, 2022, 19(11): 1213-1217.

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