Chinese Journal of Pharmacovigilance ›› 2021, Vol. 18 ›› Issue (4): 338-340.
DOI: 10.19803/j.1672-8629.2021.04.09

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Discuss about Vaccine Enhancement of Disease

WANG Yali   

  1. Center for Drug Reevaluation, NMPA, Beijing 100022, china
  • Received:2020-08-19 Online:2021-04-15 Published:2021-04-23

Abstract: Vaccine Enhancement of Disease was discussed in this paper, in order to provide information for post-marketing surveillance of SARS-CoV-2 vaccines. Methods The documents and research findings about virus vaccines and vaccine enhancement of disease (VED) were collected to analyze the safety of SARS-CoV-2 vaccines. Results and Conclusion The epidemic caused by SARS-CoV-2 has been spreading globally since 2020. As no wonder drugs are currently available, vaccine development is becoming a hot topic worldwide. Due to its uncertainty, VED is one of the common concerns during vaccine development and post-marketing surveilance should be carefully assessed in the future.

Key words: antibody-dependent enhancement, vaccine enhancement of disease, SARS-CoV-2, SARS-CoV-2 vaccines

CLC Number: